Doctor De Soto, a mouse dentist, copes with the toothaches of various animals except those with a taste for mice, until the day a fox comes to him in great pain.
Since he had a tooth pulled, Alfie refuses to go to the dentist, but now he has a dental problem, and the new dentist comes looking for him at school at a time when all the children in town have been getting eerie gifts from the Tooth Fairy.