Publisher Annotation: In the world outside of the Haven Institute, Lyra and Caelum are finding it hard to be human?and Lyra, infected at Haven with a terrible disease, finds her symptoms are growing worse. When Caelum leaves without warning, Lyra follows him, seeking a pioneering organization in Philadelphia that might have a cure. But what they uncover there is a shocking connection to their past, even as their future seems in danger of collapsing....