Pollyanna Grows Up is the first sequel to Pollyanna, and the only one written by Porter herself. Numerous following sequels have been written by various authors. Pollyanna's crippling spinal injury has been cured, and she begins to teach a new town the "glad game". She makes many friends and two of her childhood friends, Jimmy and Jamie, court her. Jimmy is an energetic, healthy young architect and Jamie is a crippled literary genius.

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David and his father set out from their idyllic mountain home to go to meet family, but enroute, David's father, who is sick dies, and David is left stranded in a little farming town. No one can read his father's handwriting, and David doesn't know his last name. A stern farmer and his wife take David in, and learn more from him than they realize! David, who counts only the sunny hours of his life, soon touches all the people's lives he meets in his...